Peptide Chemistry: Publications

  • Chao, WCH; Wade, BO; Bouchoux, C; Jones, AW; Purkiss, AG; Federico, S; O'Reilly, N; Snijders, AP; Uhlmann, F and Singleton, MR (2017)
    Structural basis of Eco1-mediated cohesin acetylation.
    Scientific Reports 7, 44313 PubMed abstract
  • Joachim, J; Razi, M; Judith, D; Wirth, M; Calamita, E; Encheva, V; Dynlacht, BD; Snijders, AP; O'Reilly, N; Jefferies, HBJ and Tooze, SA (2017)
    Centriolar satellites control GABARAP ubiquitination and GABARAP-mediated autophagy.
    Current Biology 27, 2123-2136.e2127 PubMed abstract
  • Lesbats, P; Serrao, E; Maskell, DP; Pye, VE; O'Reilly, N; Lindemann, D; Engelman, AN and Cherepanov, P (2017)
    Structural basis for spumavirus GAG tethering to chromatin.
    Proceedings of the National Academy of Sciences of the United States of America 114, 5509-5514 PubMed abstract
  • Skytte Rasmussen, M; Mouilleron, S; Kumar Shrestha, B; Wirth, M; Lee, R; Bowitz Larsen, K; Abudu Princely, Y; O'Reilly, N; Sjøttem, E; Tooze, SA; Lamark, T and Johansen, T (2017)
    ATG4B contains a C-terminal LIR motif important for binding and efficient cleavage of mammalian orthologs of yeast Atg8.
    Autophagy 13, 834-853 PubMed abstract
  • Vasileva, V; Gierlinski, M; Yue, Z; O'Reilly, N; Kitamura, E and Tanaka, TU (2017)
    Molecular mechanisms facilitating the initial kinetochore encounter with spindle microtubules.
    Journal of Cell Biology 216, 1609-1622 PubMed abstract
  • von Morgen, P; Burdova, K; Flower, TG; O'Reilly, NJ; Boulton, SJ; Smerdon, SJ; Macurek, L and Hořejší, Z (2017)
    MRE11 stability is regulated by CK2-dependent interaction with R2TP complex.
    Oncogene 36, 4943-4950 PubMed abstract
  • Soriano, EV; Ivanova, ME; Fletcher, G; Riou, P; Knowles, PP; Barnouin, K; Purkiss, A; Kostelecky, B; Saiu, P; Linch, M; Elbediwy, A; Kjær, S; O'Reilly, N; Snijders, AP; Parker, PJ; Thompson, BJ and McDonald, NQ (2016)
    aPKC inhibition by Par3 CR3 flanking regions controls substrate access and underpins apical-junctional polarization.
    Developmental Cell 38, 384-398 PubMed abstract
  • Fansa, EK; O'Reilly, NJ; Ismail, S and Wittinghofer, A (2015)
    The N- and C-terminal ends of RPGR can bind to PDE6δ.
    EMBO Reports 16, 1583-1585 PubMed abstract
  • Ivanova, ME; Fletcher, GC; O'Reilly, N; Purkiss, AG; Thompson, BJ and McDonald, NQ (2015)
    Structures of the human Pals1 PDZ domain with and without ligand suggest gated access of Crb to the PDZ peptide-binding groove.
    Acta Crystallographica. Section D, Biological Crystallography 71, 555-564 PubMed abstract
  • Kakugawa, S; Langton, PF; Zebisch, M; Howell, SA; Chang, T-H; Liu, Y; Feizi, T; Bineva, G; O'Reilly, N; Snijders, AP; Jones, EY and Vincent, J-P (2015)
    Notum deacylates Wnt proteins to suppress signalling activity.
    Nature 519, 187-192 PubMed abstract
  • Rouka, E; Simister, PC; Janning, M; Kumbrink, J; Konstantinou, T; Muniz, JRC; Joshi, D; O'Reilly, N; Volkmer, R; Ritter, B; Knapp, S; von Delft, F; Kirsch, KH and Feller, SM (2015)
    Differential recognition preferences of the three Src homology 3 (SH3) domains from the adaptor CD2-associated protein (CD2AP) and direct association with Ras and Rab interactor 3 (RIN3).
    Journal of Biological Chemistry 290, 25275-25292 PubMed abstract
  • Hořejší, Z; Stach, L; Flower, TG; Joshi, D; Flynn, H; Skehel, JM; O'Reilly, NJ; Ogrodowicz, RW; Smerdon, SJ and Boulton, SJ (2014)
    Phosphorylation-dependent PIH1D1 interactions define substrate specificity of the R2TP cochaperone complex.
    Cell Reports 7, 19-26 PubMed abstract
  • Riou, P; Kjær, S; Garg, R; Purkiss, A; George, R; Cain, RJ; Bineva, G; Reymond, N; McColl, B; Thompson, AJ; O'Reilly, N; McDonald, NQ; Parker, PJ and Ridley, AJ (2013)
    14-3-3 proteins interact with a hybrid prenyl-phosphorylation motif to inhibit G proteins.
    Cell 153, 640-653 PubMed abstract
  • Mouilleron, S; Wiezlak, M; O'Reilly, N; Treisman, R and McDonald, NQ (2012)
    Structures of the Phactr1 RPEL domain and RPEL motif complexes with G-actin reveal the molecular basis for actin binding cooperativity.
    Structure 20, 1960-1970 PubMed abstract
  • O'Reilly, N; Charbin, A; Lopez-Serra, L and Uhlmann, F (2012)
    Facile synthesis of budding yeast a-factor and its use to synchronize cells of α mating type.
    Yeast 29, 233-240 PubMed abstract

[Page last updated 1 Nov 2017]

Nicola O'Reilly

Nicola O’Reilly (Lead) 

nicola.oreilly@crick.ac.uk
+44 (0) 20 7269 3318