Research case studies Explore a selection of reports that spotlight particular areas of research at the Crick over the past five years.
Postdoctoral clinical fellows Opportunities for postdoctoral clinicians to consolidate their research experience.
Breadcrumb Flow Cytometry Flow Cytometry : Publications Lab contentLab contentIn this section Overview Training Equipment & services Publications Members The optical bench of the BD Fortessa, a cell analyser. Toggle to view hero caption Publications Displaying 1 - 10 of 335Last updated : 19 April 2024 02:00 Blimp-1 and c-Maf regulate immune gene networks to protect against distinct pathways of pathobiont-induced colitis Authors (16)Marisol Alvarez MartinezLuke Cox Claire F PearsonWilliam Branchett Probir ChakravartyXuemei Wu[...] Alejandro Suárez-Bonnet Anna MikolajczakJames Briscoe Fiona PowrieAnne O'Garra Nature Immunology Published 12 April 2024 Crick labs/ facilitiesAnne O’GarraJames BriscoeExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingFlow CytometryBiological Research FacilityAdvanced SequencingFull details Spatial architecture of myeloid and T cells orchestrates immune evasion and clinical outcome in lung cancer Authors (35)Katey Enfield Emma Colliver Claudia Lee Alastair Magness David A Moore Monica Sivakumar[...]Crispin HileyJulian DownwardErik SahaiCharles SwantonMihaela Angelova Cancer Discovery Published 6 April 2024 Crick labs/ facilitiesCharles SwantonErik SahaiJulian DownwardFlow CytometryExperimental HistopathologyScientific computingProteomicsLight MicroscopyCell ServicesBiological Research FacilityAdvanced SequencingFull details Regulation of BCR-mediated Ca2+ mobilization by MIZ1-TMBIM4 safeguards IgG1+ GC B cell-positive selection Authors (14) Lingling Zhang Amparo Toboso-Navasa Arief Gunawan Abdouramane CamaraRinako NakagawaKatja Finsterbusch[...] Martin EilersAndreas WackPavel Tolar Kai-Michael ToellnerDinis Calado Science Immunology Published 5 April 2024 Crick labs/ facilitiesAndreas WackPavel TolarDinis CaladoBioinformatics and BiostatisticsStructural BiologyLight MicroscopyFlow CytometryExperimental HistopathologyBiological Research FacilityAdvanced SequencingFull details CDK activity at the centrosome regulates the cell cycle Authors (6)Emma RobertsJessica GreenwoodNitin Kapadia Tania AuchynnikavaSaz BasuPaul Nurse Cell Reports Published 23 April 2024 Crick labs/ facilitiesPaul NurseProteomicsLight MicroscopyFlow CytometryFull details Practicalities of cell sorting Authors (6) Mark CheethamDerek Davies Christopher Hall Charlotte Christie Petersen Reiner Schulte Rachael Walker Methods in Molecular Biology Published 26 March 2024 Crick labs/ facilitiesFlow CytometryFull details FOXL2 interaction with different binding partners regulates the dynamics of ovarian development Authors (7)Roberta MigaleMichelle Neumann Richard MitterMahmoud-Reza Rafiee Sophie WoodJessica OlsenRobin Lovell-Badge Science advances Published 22 March 2024 Crick labs/ facilitiesJernej UleRobin Lovell-BadgeGenetic Modification ServiceBioinformatics and BiostatisticsProteomicsLight MicroscopyFlow CytometryExperimental HistopathologyBiological Research FacilityAdvanced SequencingFull details TOR regulates variability of protein synthesis rates Authors (2)Clovis BasierPaul Nurse The EMBO Journal Published 16 April 2024 Crick labs/ facilitiesPaul NurseLight MicroscopyFlow CytometryFull details Evaluation of sort recovery via Rmax Authors (6) Alexis Perez-Gonzalez Telma Lopes Lola Martinez Claudia Bispo Rui GardnerAndy Riddell Current Protocols Published 16 February 2024 Crick labs/ facilitiesFlow CytometryFull details Distinct ontogenetic lineages dictate cDC2 heterogeneity Authors (15)Carlos Munoz MinuttiCecile PiotMariana Pereira Da Costa Probir ChakravartyNeil RogersHector Huerga Encabo[...] Jean LanghorneDominique Bonnet Marc Dalod Elena TomaselloCaetano Reis e Sousa Nature Immunology Published 1 March 2024 Crick labs/ facilitiesCaetano Reis e SousaJean LanghorneGeorge KassiotisDominique BonnetBioinformatics and BiostatisticsFlow CytometryBiological Research FacilityAdvanced SequencingFull details The artificial intelligence-based model ANORAK improves histopathological grading of lung adenocarcinoma Authors (20) Xiaoxi Pan Khalid AbdulJabbar Jose Coelho-Lima Anca-Ioana Grapa Hanyun Zhang Alvin Ho Kwan Cheung[...] TRACERx ConsortiumCharles Swanton Yinyin Yuan John Le Quesne David A Moore Nature Cancer Published 1 February 2024 Crick labs/ facilitiesPeter Van LooSamra TurajlicCharles SwantonErik SahaiGeorge KassiotisFlow CytometryExperimental HistopathologyBiological Research FacilityBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details Pagination Current page 1 Page 2 Page 3 Page 4 Page 5 Page 6 Page 7 Page 8 Page 9 … Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Blimp-1 and c-Maf regulate immune gene networks to protect against distinct pathways of pathobiont-induced colitis Authors (16)Marisol Alvarez MartinezLuke Cox Claire F PearsonWilliam Branchett Probir ChakravartyXuemei Wu[...] Alejandro Suárez-Bonnet Anna MikolajczakJames Briscoe Fiona PowrieAnne O'Garra Nature Immunology Published 12 April 2024 Crick labs/ facilitiesAnne O’GarraJames BriscoeExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingFlow CytometryBiological Research FacilityAdvanced SequencingFull details
Spatial architecture of myeloid and T cells orchestrates immune evasion and clinical outcome in lung cancer Authors (35)Katey Enfield Emma Colliver Claudia Lee Alastair Magness David A Moore Monica Sivakumar[...]Crispin HileyJulian DownwardErik SahaiCharles SwantonMihaela Angelova Cancer Discovery Published 6 April 2024 Crick labs/ facilitiesCharles SwantonErik SahaiJulian DownwardFlow CytometryExperimental HistopathologyScientific computingProteomicsLight MicroscopyCell ServicesBiological Research FacilityAdvanced SequencingFull details
Regulation of BCR-mediated Ca2+ mobilization by MIZ1-TMBIM4 safeguards IgG1+ GC B cell-positive selection Authors (14) Lingling Zhang Amparo Toboso-Navasa Arief Gunawan Abdouramane CamaraRinako NakagawaKatja Finsterbusch[...] Martin EilersAndreas WackPavel Tolar Kai-Michael ToellnerDinis Calado Science Immunology Published 5 April 2024 Crick labs/ facilitiesAndreas WackPavel TolarDinis CaladoBioinformatics and BiostatisticsStructural BiologyLight MicroscopyFlow CytometryExperimental HistopathologyBiological Research FacilityAdvanced SequencingFull details
CDK activity at the centrosome regulates the cell cycle Authors (6)Emma RobertsJessica GreenwoodNitin Kapadia Tania AuchynnikavaSaz BasuPaul Nurse Cell Reports Published 23 April 2024 Crick labs/ facilitiesPaul NurseProteomicsLight MicroscopyFlow CytometryFull details
Practicalities of cell sorting Authors (6) Mark CheethamDerek Davies Christopher Hall Charlotte Christie Petersen Reiner Schulte Rachael Walker Methods in Molecular Biology Published 26 March 2024 Crick labs/ facilitiesFlow CytometryFull details
FOXL2 interaction with different binding partners regulates the dynamics of ovarian development Authors (7)Roberta MigaleMichelle Neumann Richard MitterMahmoud-Reza Rafiee Sophie WoodJessica OlsenRobin Lovell-Badge Science advances Published 22 March 2024 Crick labs/ facilitiesJernej UleRobin Lovell-BadgeGenetic Modification ServiceBioinformatics and BiostatisticsProteomicsLight MicroscopyFlow CytometryExperimental HistopathologyBiological Research FacilityAdvanced SequencingFull details
TOR regulates variability of protein synthesis rates Authors (2)Clovis BasierPaul Nurse The EMBO Journal Published 16 April 2024 Crick labs/ facilitiesPaul NurseLight MicroscopyFlow CytometryFull details
Evaluation of sort recovery via Rmax Authors (6) Alexis Perez-Gonzalez Telma Lopes Lola Martinez Claudia Bispo Rui GardnerAndy Riddell Current Protocols Published 16 February 2024 Crick labs/ facilitiesFlow CytometryFull details
Distinct ontogenetic lineages dictate cDC2 heterogeneity Authors (15)Carlos Munoz MinuttiCecile PiotMariana Pereira Da Costa Probir ChakravartyNeil RogersHector Huerga Encabo[...] Jean LanghorneDominique Bonnet Marc Dalod Elena TomaselloCaetano Reis e Sousa Nature Immunology Published 1 March 2024 Crick labs/ facilitiesCaetano Reis e SousaJean LanghorneGeorge KassiotisDominique BonnetBioinformatics and BiostatisticsFlow CytometryBiological Research FacilityAdvanced SequencingFull details
The artificial intelligence-based model ANORAK improves histopathological grading of lung adenocarcinoma Authors (20) Xiaoxi Pan Khalid AbdulJabbar Jose Coelho-Lima Anca-Ioana Grapa Hanyun Zhang Alvin Ho Kwan Cheung[...] TRACERx ConsortiumCharles Swanton Yinyin Yuan John Le Quesne David A Moore Nature Cancer Published 1 February 2024 Crick labs/ facilitiesPeter Van LooSamra TurajlicCharles SwantonErik SahaiGeorge KassiotisFlow CytometryExperimental HistopathologyBiological Research FacilityBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details
