Moritz Treeck: Publications

  • Child, MA; Garland, M; Foe, I; Madzelan, P; Treeck, M; van der Linden, WA; Oresic Bender, K; Weerapana, E; Wilson, MA; Boothroyd, JC; Reese, ML and Bogyo, M (2017)
    Toxoplasma DJ-1 regulates organelle secretion by a direct interaction with calcium-dependent protein kinase 1.
    mBio 8, e02189-02116 PubMed abstract
  • Jones, ML; Das, S; Belda, H; Collins, CR; Blackman, MJ and Treeck, M (2016)
    A versatile strategy for rapid conditional genome engineering using loxP sites in a small synthetic intron in Plasmodium falciparum.
    Scientific Reports 6, 21800 PubMed abstract
  • Krishnamurthy, S; Deng, B; del Rio, R; Buchholz, KR; Treeck, M; Urban, S; Boothroyd, J; Lam, Y-W and Ward, GE (2016)
    Not a simple tether: binding of Toxoplasma gondii AMA1 to RON2 during invasion protects AMA1 from rhomboid-mediated cleavage and leads to dephosphorylation of its cytosolic tail.
    mBio 7, e00754-00716 PubMed abstract
  • Das, S; Hertrich, N; Perrin, AJ; Withers-Martinez, C; Collins, CR; Jones, ML; Watermeyer, JM; Fobes, ET; Martin, SR; Saibil, HR; Wright, GJ; Treeck, M; Epp, C and Blackman, MJ (2015)
    Processing of Plasmodium falciparum merozoite surface protein MSP1 activates a spectrin-binding function enabling parasite egress from RBCs.
    Cell Host & Microbe 18, 433-444 PubMed abstract
  • Gaji, RY; Johnson, DE; Treeck, M; Wang, M; Hudmon, A and Arrizabalaga, G (2015)
    Phosphorylation of a myosin motor by TgCDPK3 facilitates rapid initiation of motility during Toxoplasma gondii egress.
    PLOS Pathogens 11, e1005268 PubMed abstract
  • Pernas, L; Adomako-Ankomah, Y; Shastri, AJ; Ewald, SE; Treeck, M; Boyle, JP and Boothroyd, JC (2014)
    Toxoplasma effector MAF1 mediates recruitment of host mitochondria and impacts the host response.
    PLOS Biology 12, e1001845 PubMed abstract
  • Treeck, M; Sanders, JL; Gaji, RY; LaFavers, KA; Child, MA; Arrizabalaga, G; Elias, JE and Boothroyd, JC (2014)
    The calcium-dependent protein kinase 3 of Toxoplasma influences basal calcium levels and functions beyond egress as revealed by quantitative phosphoproteome analysis.
    PLOS Pathogens 10, e1004197 PubMed abstract
  • Hoeijmakers, WAM; Salcedo-Amaya, AM; Smits, AH; Françoijs, K-J; Treeck, M; Gilberger, T-W; Stunnenberg, HG and Bártfai, R (2013)
    H2A.Z/H2B.Z double-variant nucleosomes inhabit the AT-rich promoter regions of the Plasmodium falciparum genome.
    Molecular Microbiology 87, 1061-1073 PubMed abstract
  • Poukchanski, A; Fritz, HM; Tonkin, ML; Treeck, M; Boulanger, MJ and Boothroyd, JC (2013)
    Toxoplasma gondii sporozoites invade host cells using two novel paralogues of RON2 and AMA1.
    PLOS ONE 8, e70637 PubMed abstract
  • Garrison, E; Treeck, M; Ehret, E; Butz, H; Garbuz, T; Oswald, BP; Settles, M; Boothroyd, J and Arrizabalaga, G (2012)
    A forward genetic screen reveals that calcium-dependent protein kinase 3 regulates egress in Toxoplasma.
    PLOS Pathogens 8, e1003049 PubMed abstract
  • Lasonder, E; Treeck, M; Alam, M and Tobin, AB (2012)
    Insights into the Plasmodium falciparum schizont phospho-proteome.
    Microbes and Infection 14, 811-819 PubMed abstract
  • Yahata, K; Treeck, M; Culleton, R; Gilberger, T-W and Kaneko, O (2012)
    Time-lapse imaging of red blood cell invasion by the rodent malaria parasite Plasmodium yoelii.
    PLOS ONE 7, e50780 PubMed abstract
  • Treeck, M; Sanders, JL; Elias, JE and Boothroyd, JC (2011)
    The phosphoproteomes of Plasmodium falciparum and Toxoplasma gondii reveal unusual adaptations within and beyond the parasites' boundaries.
    Cell Host & Microbe 10, 410-419 PubMed abstract
  • Tyler, JS; Treeck, M and Boothroyd, JC (2011)
    Focus on the ringleader: the role of AMA1 in apicomplexan invasion and replication.
    Trends in Parasitology 27, 410-420 PubMed abstract
  • Bártfai, R; Hoeijmakers, WAM; Salcedo-Amaya, AM; Smits, AH; Janssen-Megens, E; Kaan, A; Treeck, M; Gilberger, T-W; Françoijs, K-J and Stunnenberg, HG (2010)
    H2A.Z demarcates intergenic regions of the Plasmodium falciparum epigenome that are dynamically marked by H3K9ac and H3K4me3.
    PLOS Pathogens 6, e1001223 PubMed abstract
  • Leykauf, K; Treeck, M; Gilson, PR; Nebl, T; Braulke, T; Cowman, AF; Gilberger, TW and Crabb, BS (2010)
    Protein kinase A dependent phosphorylation of apical membrane antigen 1 plays an important role in erythrocyte invasion by the malaria parasite.
    PLOS Pathogens 6, e1000941 PubMed abstract

[Page last updated 1 Nov 2017]

Moritz Treeck

moritz.treeck@crick.ac.uk
+44 (0)20 379 62345

  • Qualifications and history
  • 2009 PhD Bernhard Nocht Institute for Tropical Medicine Hamburg, University of Hamburg, Germany
  • 2009- 2013 Postdoctoral fellow, Stanford University, Stanford, USA
  • 2014 Group Leader, Medical Research Council National Institute for Medical Research, London, UK
  • 2015 Group Leader, the Francis Crick Institute, London, UK