Barry Thompson: Publications

  • Aguilar-Aragon, M; Elbediwy, A; Foglizzo, V; Fletcher, GC; Li, VSW and Thompson, BJ (2018)
    Pak1 kinase maintains apical membrane identity in epithelia.
    Cell Reports 22, 1639-1646 PubMed abstract
  • Elbediwy, A and Thompson, BJ (2018)
    Evolution of mechanotransduction via YAP/TAZ in animal epithelia.
    Current Opinion in Cell Biology 51, 117-123 PubMed abstract
  • Fletcher, GC; Diaz-de-la-Loza, M-d-C; Borreguero-Muñoz, N; Holder, M; Aguilar-Aragon, M and Thompson, BJ (2018)
    Mechanical strain regulates the Hippo pathway in Drosophila.
    Development 145, dev159467 PubMed abstract
  • Thompson, BJ and Giancotti, FG (2018)
    Editorial overview: Cell signalling: Signal transduction to the nucleus, cytoskeleton, and organelles.
    Current Opinion in Cell Biology 51, iv-vii PubMed abstract
  • Diaz de la Loza, MC and Thompson, BJ (2016)
    Forces shaping the Drosophila wing.
    Mechanisms of Development 144, 23-32 PubMed abstract
  • Elbediwy, A; Vincent-Mistiaen, ZI; Spencer-Dene, B; Stone, RK; Boeing, S; Wculek, SK; Cordero, J; Tan, EH; Ridgway, R; Brunton, VG; Sahai, E; Gerhardt, H; Behrens, A; Malanchi, I; Sansom, OJ and Thompson, BJ (2016)
    Integrin signalling regulates YAP and TAZ to control skin homeostasis.
    Development 143, 1674-1687 PubMed abstract
  • Elbediwy, A; Vincent-Mistiaen, ZI and Thompson, BJ (2016)
    YAP and TAZ in epithelial stem cells: A sensor for cell polarity, mechanical forces and tissue damage.
    Bioessays 38, 644-653 PubMed abstract
  • Khanal, I; Elbediwy, A; Diaz de la Loza, MDC; Fletcher, GC and Thompson, BJ (2016)
    Shot and Patronin polarise microtubules to direct membrane traffic and biogenesis of microvilli in epithelia.
    Journal of Cell Science 129, 2651-2659 PubMed abstract
  • Soriano, EV; Ivanova, ME; Fletcher, G; Riou, P; Knowles, PP; Barnouin, K; Purkiss, A; Kostelecky, B; Saiu, P; Linch, M; Elbediwy, A; Kjær, S; O'Reilly, N; Snijders, AP; Parker, PJ; Thompson, BJ and McDonald, NQ (2016)
    aPKC inhibition by Par3 CR3 flanking regions controls substrate access and underpins apical-junctional polarization.
    Developmental Cell 38, 384-398 PubMed abstract
  • Srinivasan, N; Gordon, O; Ahrens, S; Franz, A; Deddouche, S; Chakravarty, P; Phillips, D; Yunus, AA; Rosen, MK; Valente, RS; Teixeira, L; Thompson, B; Dionne, MS; Wood, W and Reis e Sousa, C (2016)
    Actin is an evolutionarily-conserved damage-associated molecular pattern that signals tissue injury in Drosophila melanogaster.
    eLife 5, e19662 PubMed abstract
  • Bell, GP; Fletcher, GC; Brain, R and Thompson, BJ (2015)
    Aurora kinases phosphorylate Lgl to induce mitotic spindle orientation in Drosophila epithelia.
    Current Biology 25, 61-68 PubMed abstract
  • Fletcher, GC; Elbediwy, A; Khanal, I; Ribeiro, PS; Tapon, N and Thompson, BJ (2015)
    The Spectrin cytoskeleton regulates the Hippo signalling pathway.
    EMBO Journal 34, 940-954 PubMed abstract
  • Ivanova, ME; Fletcher, GC; O'Reilly, N; Purkiss, AG; Thompson, BJ and McDonald, NQ (2015)
    Structures of the human Pals1 PDZ domain with and without ligand suggest gated access of Crb to the PDZ peptide-binding groove.
    Acta Crystallographica. Section D, Biological Crystallography 71, 555-564 PubMed abstract
  • Madsen, CD; Hooper, S; Tozluoglu, M; Bruckbauer, A; Fletcher, G; Erler, JT; Bates, PA; Thompson, B and Sahai, E (2015)
    STRIPAK components determine mode of cancer cell migration and metastasis.
    Nature Cell Biology 17, 68-80 PubMed abstract
  • Ray, RP; Matamoro-Vidal, A; Ribeiro, PS; Tapon, N; Houle, D; Salazar-Ciudad, I and Thompson, BJ (2015)
    Patterned anchorage to the apical extracellular matrix defines tissue shape in the developing appendages of Drosophila.
    Developmental Cell 34, 310-322 PubMed abstract
  • Thompson, BJ (2015)
    From Hippos to Yorkies in one pathway.
    Nature Reviews Molecular Cell Biology 16, 392 PubMed abstract
  • Thompson, BJ and Sahai, E (2015)
    MST kinases in development and disease.
    Journal of Cell Biology 210, 871-882 PubMed abstract
  • Bell, GP and Thompson, BJ (2014)
    Colorectal cancer progression: lessons from Drosophila?
    Seminars in Cell & Developmental Biology 28, 70-77 PubMed abstract
  • Rodrigues-Campos, M and Thompson, BJ (2014)
    The ubiquitin ligase FbxL7 regulates the Dachsous-Fat-Dachs system in Drosophila.
    Development 141, 4098-4103 PubMed abstract
  • Lucas, EP; Khanal, I; Gaspar, P; Fletcher, GC; Polesello, C; Tapon, N and Thompson, BJ (2013)
    The Hippo pathway polarizes the actin cytoskeleton during collective migration of Drosophila border cells.
    Journal of Cell Biology 201, 875-885 PubMed abstract
  • Mao, Y; Tournier, AL; Hoppe, A; Kester, L; Thompson, BJ and Tapon, N (2013)
    Differential proliferation rates generate patterns of mechanical tension that orient tissue growth.
    EMBO Journal 32, 2790-2803 PubMed abstract
  • Sidor, CM; Brain, R and Thompson, BJ (2013)
    Mask proteins are cofactors of Yorkie/YAP in the Hippo pathway.
    Current Biology 23, 223-228 PubMed abstract
  • Thompson, BJ (2013)
    Cell polarity: models and mechanisms from yeast, worms and flies.
    Development 140, 13-21 PubMed abstract
  • Thompson, BJ; Pichaud, F and Röper, K (2013)
    Sticking together the Crumbs - an unexpected function for an old friend.
    Nature Reviews Molecular Cell Biology 14, 307-314 PubMed abstract
  • Ahrens, S; Zelenay, S; Sancho, D; Hanč, P; Kjær, S; Feest, C; Fletcher, G; Durkin, C; Postigo, A; Skehel, M; Batista, F; Thompson, B; Way, M; Reis e Sousa, C and Schulz, O (2012)
    F-actin is an evolutionarily conserved damage-associated molecular pattern recognized by DNGR-1, a receptor for dead cells.
    Immunity 36, 635-645 PubMed abstract
  • Fletcher, GC; Lucas, EP; Brain, R; Tournier, A and Thompson, BJ (2012)
    Positive feedback and mutual antagonism combine to polarize Crumbs in the Drosophila follicle cell epithelium.
    Current Biology 22, 1116-1122 PubMed abstract
  • Thompson, B (2012)
    Barry Thompson: The delicate choreography in growing epithelia. Interview by Caitlin Sedwick.
    Journal of Cell Biology 198, 268-269 PubMed abstract
  • Thompson, BJ; Perez, F and Vaccari, T (2012)
    The young and happy marriage of membrane traffic and cell polarity.
    EMBO Reports 13, 670-672 PubMed abstract
  • Mao, Y; Tournier, AL; Bates, PA; Gale, JE; Tapon, N and Thompson, BJ (2011)
    Planar polarization of the atypical myosin Dachs orients cell divisions in Drosophila.
    Genes & Development 25, 131-136 PubMed abstract
  • Zhang, W; Thompson, BJ; Hietakangas, V and Cohen, SM (2011)
    MAPK/ERK signaling regulates insulin sensitivity to control glucose metabolism in Drosophila.
    PLOS Genetics 7, e1002429 PubMed abstract
  • Genevet, A; Wehr, MC; Brain, R; Thompson, BJ and Tapon, N (2010)
    Kibra is a regulator of the Salvador/Warts/Hippo signaling network.
    Developmental Cell 18, 300-308 PubMed abstract
  • Thompson, BJ (2010)
    Developmental control of cell growth and division in Drosophila.
    Current Opinion in Cell Biology 22, 788-794 PubMed abstract
  • Thompson, BJ (2010)
    Mal/SRF is dispensable for cell proliferation in Drosophila.
    PLOS ONE 5, e10077 PubMed abstract

[Page last updated 1 Jun 2018]

Barry Thompson
+44 (0)20 379 61337

  • Qualifications and history
  • 2004 PhD, Cambridge University, UK
  • 2004 Postdoctoral Fellow, European Molecular Biology Laboratory, Germany
  • 2006 Visiting Scientist, Research Institute of Molecular Pathology, Austria
  • 2007 Established lab at the London Research Institute, Cancer Research UK
  • 2015 Group Leader, the Francis Crick Institute, London, UK