Gitta Stockinger: Publications

  • Hirota, K; Hashimoto, M; Ito, Y; Matsuura, M; Ito, H; Tanaka, M; Watanabe, H; Kondoh, G; Tanaka, A; Yasuda, K; Kopf, M; Potocnik, AJ; Stockinger, B; Sakaguchi, N and Sakaguchi, S (2018)
    Autoimmune Th17 cells induced synovial stromal and innate lymphoid cell secretion of the cytokine GM-CSF to initiate and augment autoimmune arthritis.
    Immunity 48, 1-13 PubMed abstract
  • Schiering, C; Vonk, A; Das, S; Stockinger, B and Wincent, E (2018)
    Cytochrome P4501-inhibiting chemicals amplify aryl hydrocarbon receptor activation and IL-22 production in T helper 17 cells.
    Biochemical Pharmacology 151, 47-58 PubMed abstract
  • Di Meglio, P and Nestle, FO (2017)
    Immunopathogenesis of psoriasis.
    In: Clinical and Basic Immunodermatology. Edited by Gaspari, A; Tyring, S and Kaplan, D. Second edition.
    Springer, 2017. 373-395.
  • Entwistle, LJ; Pelly, VS; Coomes, SM; Kannan, Y; Perez-Lloret, J; Czieso, S; Silva dos Santos, M; MacRae, JI; Collinson, L; Sesay, A; Nikolov, N; Metidji, A; Helmby, H; Hui, DY and Wilson, MS (2017)
    Epithelial-cell-derived phospholipase A2 group 1B is an endogenous anthelmintic.
    Cell Host & Microbe 22, 484-493.e485 PubMed abstract
  • Gialitakis, M; Tolaini, M; Li, Y; Pardo, M; Yu, L; Toribio, A; Choudhary, JS; Niakan, K; Papayannopoulos, V and Stockinger, B (2017)
    Activation of the aryl hydrocarbon receptor interferes with early embryonic development.
    Stem Cell Reports 9, 1377-1386 PubMed abstract
  • Mahil, SK; Catapano, M; Di Meglio, P; Dand, N; Ahlfors, H; Carr, IM; Smith, CH; Trembath, RC; Peakman, M; Wright, J; Ciccarelli, FD; Barker, JN and Capon, F (2017)
    An analysis of IL-36 signature genes and individuals with IL1RL2 knockout mutations validates IL-36 as a psoriasis therapeutic target.
    Science Translational Medicine 9, eaan2514 PubMed abstract
  • Miralles, M; Eixarch, H; Tejero, M; Costa, C; Hirota, K; Castaño, AR; Puig, M; Stockinger, G; Montalban, X; Bosch, A; Espejo, C and Chillon, M (2017)
    Clinical and histopathological amelioration of experimental autoimmune encephalomyelitis by AAV vectors expressing a soluble interleukin-23 receptor.
    Neurotherapeutics 14, 1095-1106 PubMed abstract
  • Papotto, PH; Gonçalves-Sousa, N; Schmolka, N; Iseppon, A; Mensurado, S; Stockinger, B; Ribot, JC and Silva-Santos, B (2017)
    IL-23 drives differentiation of peripheral γδ17 T cells from adult bone marrow-derived precursors.
    EMBO Reports 18, 1957-1967 PubMed abstract
  • Pelly, VS; Coomes, SM; Kannan, Y; Gialitakis, M; Entwistle, LJ; Perez-Lloret, J; Czieso, S; Okoye, IS; Rückerl, D; Allen, JE; Brombacher, F and Wilson, MS (2017)
    Interleukin 4 promotes the development of ex-Foxp3 Th2 cells during immunity to intestinal helminths.
    Journal of Experimental Medicine 214, 1809-1826 PubMed abstract
  • Schiering, C; Wincent, E; Metidji, A; Iseppon, A; Li, Y; Potocnik, AJ; Omenetti, S; Henderson, CJ; Wolf, CR; Nebert, DW and Stockinger, B (2017)
    Feedback control of AHR signalling regulates intestinal immunity.
    Nature 542, 242-245 PubMed abstract
  • Stockinger, B and Omenetti, S (2017)
    The dichotomous nature of T helper 17 cells.
    Nature Reviews Immunology 17, 535-544 PubMed abstract
  • Villa, M; Gialitakis, M; Tolaini, M; Ahlfors, H; Henderson, CJ; Wolf, CR; Brink, R and Stockinger, B (2017)
    Aryl hydrocarbon receptor is required for optimal B-cell proliferation.
    EMBO Journal 36, 116-128 PubMed abstract
  • Krebs, CF; Paust, H-J; Krohn, S; Koyro, T; Brix, SR; Riedel, J-H; Bartsch, P; Wiech, T; Meyer-Schwesinger, C; Huang, J; Fischer, N; Busch, P; Mittrücker, H-W; Steinhoff, U; Stockinger, B; Perez, LG; Wenzel, UO; Janneck, M; Steinmetz, OM; Gagliani, N; Stahl, RAK; Huber, S; Turner, J-E and Panzer, U (2016)
    Autoimmune renal disease is exacerbated by S1P-receptor-1-dependent intestinal Th17 cell migration to the kidney.
    Immunity 45, 1078-1092 PubMed abstract
  • Krebs, CF; Turner, J-E; Paust, H-J; Kapffer, S; Koyro, T; Krohn, S; Ufer, F; Friese, MA; Flavell, RA; Stockinger, B; Steinmetz, OM; Stahl, RAK; Huber, S and Panzer, U (2016)
    Plasticity of Th17 cells in autoimmune kidney diseases.
    Journal of Immunology 197, 449-457 PubMed abstract
  • Mahil, SK; Twelves, S; Farkas, K; Setta-Kaffetzi, N; Burden, AD; Gach, JE; Irvine, AD; Képíró, L; Mockenhaupt, M; Oon, HH; Pinner, J; Ranki, A; Seyger, MMB; Soler-Palacin, P; Storan, ER; Tan, ES; Valeyrie-Allanore, L; Young, HS; Trembath, RC; Choon, S-E; Szell, M; Bata-Csorgo, Z; Smith, CH; Di Meglio, P; Barker, JN and Capon, F (2016)
    AP1S3 mutations cause skin autoinflammation by disrupting keratinocyte autophagy and up-regulating IL-36 production.
    Journal of Investigative Dermatology 136, 2251-2259 PubMed abstract
  • Tuomela, S; Rautio, S; Ahlfors, H; Öling, V; Salo, V; Ullah, U; Chen, Z; Hämälistö, S; Tripathi, SK; Äijö, T; Rasool, O; Soueidan, H; Wessels, L; Stockinger, B; Lähdesmäki, H and Lahesmaa, R (2016)
    Comparative analysis of human and mouse transcriptomes of Th17 cell priming.
    Oncotarget 7, 13416-13428 PubMed abstract
  • Villa, M; Crotta, S; Dingwell, KS; Hirst, EMA; Gialitakis, M; Ahlfors, H; Smith, JC; Stockinger, B and Wack, A (2016)
    The aryl hydrocarbon receptor controls cyclin O to promote epithelial multiciliogenesis.
    Nature Communications 7, 12652 PubMed abstract
  • Gagliani, N; Vesely, MCA; Iseppon, A; Brockmann, L; Xu, H; Palm, NW; de Zoete, MR; Licona-Limón, P; Paiva, RS; Ching, T; Weaver, C; Zi, X; Pan, X; Fan, R; Garmire, LX; Cotton, MJ; Drier, Y; Bernstein, B; Geginat, J; Stockinger, B; Esplugues, E; Huber, S and Flavell, RA (2015)
    Tʜ17 cells transdifferentiate into regulatory T cells during resolution of inflammation.
    Nature 523, 221-225 PubMed abstract
  • Gartlan, KH; Markey, KA; Varelias, A; Bunting, MD; Koyama, M; Kuns, RD; Raffelt, NC; Olver, SD; Lineburg, KE; Cheong, M; Teal, BE; Lor, M; Comerford, I; Teng, MWL; Smyth, MJ; McCluskey, J; Rossjohn, J; Stockinger, B; Boyle, GM; Lane, SW; Clouston, AD; McColl, SR; MacDonald, KPA and Hill, GR (2015)
    Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8+ T cells that induce GVHD without antileukemic effects.
    Blood 126, 1609-1620 PubMed abstract
  • Intosalmi, J; Ahlfors, H; Rautio, S; Mannerstöm, H; Chen, ZJ; Lahesmaa, R; Stockinger, B and Lähdesmäki, H (2015)
    Analyzing Th17 cell differentiation dynamics using a novel integrative modeling framework for time-course RNA sequencing data.
    BMC Systems Biology 9, 81 PubMed abstract
  • Ahlfors, H; Morrison, PJ; Duarte, JH; Li, Y; Biro, J; Tolaini, M; Di Meglio, P; Potocnik, AJ and Stockinger, B (2014)
    IL-22 fate reporter reveals origin and control of IL-22 production in homeostasis and infection.
    Journal of Immunology 193, 4602-4613 PubMed abstract
  • Di Meglio, P; Duarte, JH; Ahlfors, H; Owens, NDL; Li, Y; Villanova, F; Tosi, I; Hirota, K; Nestle, FO; Mrowietz, U; Gilchrist, MJ and Stockinger, B (2014)
    Activation of the aryl hydrocarbon receptor dampens the severity of inflammatory skin conditions.
    Immunity 40, 989-1001 PubMed abstract
  • Di Meglio, P; Villanova, F and Nestle, FO (2014)
    Cold Spring Harbor Perspectives in Medicine 4, a015354 PubMed abstract
  • Sriskantharajah, S; Gückel, E; Tsakiri, N; Kierdorf, K; Brender, C; Ben-Addi, A; Veldhoen, M; Tsichlis, PN; Stockinger, B; O'Garra, A; Prinz, M; Kollias, G and Ley, SC (2014)
    Regulation of experimental autoimmune encephalomyelitis by TPL-2 kinase.
    Journal of Immunology 192, 3518-3529 PubMed abstract
  • Stockinger, B; Di Meglio, P; Gialitakis, M and Duarte, JH (2014)
    The aryl hydrocarbon receptor: multitasking in the immune system.
    Annual Review of Immunology 32, 403-432 PubMed abstract
  • Sutherland, TE; Logan, N; Rückerl, D; Humbles, AA; Allan, SM; Papayannopoulos, V; Stockinger, B; Maizels, RM and Allen, JE (2014)
    Chitinase-like proteins promote IL-17-mediated neutrophilia in a tradeoff between nematode killing and host damage.
    Nature Immunology 15, 1116-1125 PubMed abstract
  • Buckley, CD; Gilroy, DW; Serhan, CN; Stockinger, B and Tak, PP (2013)
    The resolution of inflammation.
    Nature Reviews Immunology 13, 10.1111/j.1469-7580.2012.01526.x PubMed abstract
  • Duarte, JH; Di Meglio, P; Hirota, K; Ahlfors, H and Stockinger, B (2013)
    Differential influences of the aryl hydrocarbon receptor on Th17 mediated responses in vitro and in vivo.
    PLOS ONE 8, e79819 PubMed abstract
  • Hirota, K; Turner, J-E; Villa, M; Duarte, JH; Demengeot, J; Steinmetz, OM and Stockinger, B (2013)
    Plasticity of TH17 cells in Peyer's patches is responsible for the induction of T cell-dependent IgA responses.
    Nature Immunology 14, 372-379 PubMed abstract
  • Krebs, CF; Kapffer, S; Paust, H-J; Schmidt, T; Bennstein, SB; Peters, A; Stege, G; Brix, SR; Meyer-Schwesinger, C; Müller, R-U; Turner, J-E; Steinmetz, OM; Wolf, G; Stahl, RAK and Panzer, U (2013)
    MicroRNA-155 drives TH17 immune response and tissue injury in experimental crescentic GN.
    Journal of the American Society of Nephrology 24, 1955-1965 PubMed abstract
  • Morrison, PJ; Bending, D; Fouser, LA; Wright, JF; Stockinger, B; Cooke, A and Kullberg, MC (2013)
    Th17-cell plasticity in Helicobacter hepaticus-induced intestinal inflammation.
    Mucosal Immunology 6, 1143-1156 PubMed abstract
  • Roetynck, S; Olotu, A; Simam, J; Marsh, K; Stockinger, B; Urban, B and Langhorne, J (2013)
    Phenotypic and functional profiling of CD4 T cell compartment in distinct populations of healthy adults with different antigenic exposure.
    PLOS ONE 8, e55195 PubMed abstract
  • Stockinger, B (2013)
    Open questions: a few that need answers in immunology.
    BMC Biology 11, 115 PubMed abstract
  • Turner, J-E; Morrison, PJ; Wilhelm, C; Wilson, M; Ahlfors, H; Renauld, J-C; Panzer, U; Helmby, H and Stockinger, B (2013)
    IL-9-mediated survival of type 2 innate lymphoid cells promotes damage control in helminth-induced lung inflammation.
    Journal of Experimental Medicine 210, 2951-2965 PubMed abstract
  • Turner, J-E; Stockinger, B and Helmby, H (2013)
    IL-22 mediates goblet cell hyperplasia and worm expulsion in intestinal helminth infection.
    PLOS Pathogens 9, e1003698 PubMed abstract
  • Mastelic, B; Freitas do Rosario, AP; Veldhoen, M; Renauld, J-C; Jarra, W; Sponaas, A-M; Roetynck, S; Stockinger, B and Langhorne, J (2012)
    IL-22 protects against liver pathology and lethality of an experimental blood-stage malaria infection.
    Frontiers in Immunology 3, 00085 PubMed abstract
  • Tuomela, S; Salo, V; Tripathi, SK; Chen, Z; Laurila, K; Gupta, B; Äijö, T; Oikari, L; Stockinger, B; Lähdesmäki, H and Lahesmaa, R (2012)
    Identification of early gene expression changes during human Th17 cell differentiation.
    Blood 119, e151-e160 PubMed abstract
  • Wilhelm, C; Turner, JE; Van Snick, J and Stockinger, B (2012)
    The many lives of IL-9: a question of survival?
    Nature Immunology 13, 637-641 PubMed abstract
  • Hirota, K; Ahlfors, H; Duarte, JH and Stockinger, B (2011)
    Regulation and function of innate and adaptive interleukin-17-producing cells.
    EMBO Reports 131, 113-120 PubMed abstract
  • Hirota, K; Duarte, JH; Veldhoen, M; Hornsby, E; Li, Y; Cua, DJ; Ahlfors, H; Wilhelm, C; Tolaini, M; Menzel, U; Garefalaki, A; Potocnik, AJ and Stockinger, B (2011)
    Fate mapping of IL-17-producing T cells in inflammatory responses.
    Nature Immunology 12, 255-264 PubMed abstract
  • Li, Y; Innocentin, S; Withers, DR; Roberts, NA; Gallagher, AR; Grigorieva, EF; Wilhelm, C and Veldhoen, M (2011)
    Exogenous stimuli maintain intraepithelial lymphocytes via aryl hydrocarbon receptor activation.
    Cell 147, 629-640 PubMed abstract
  • Stockinger, B; Hirota, K; Duarte, J and Veldhoen, M (2011)
    External influences on the immune system via activation of the aryl hydrocarbon receptor.
    Seminars in Immunology 23, 99-105 PubMed abstract
  • Wilhelm, C; Hirota, K; Stieglitz, B; Van Snick, J; Tolaini, M; Lahl, K; Sparwasser, T; Helmby, H and Stockinger, B (2011)
    An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammation.
    Nature Immunology 12, 1071-1077 PubMed abstract
  • Burton, OT; Zaccone, P; Phillips, JM; De La Peña, H; Fehérvári, Z; Azuma, M; Gibbs, S; Stockinger, B and Cooke, A (2010)
    Roles for TGF-β and programmed cell death 1 ligand 1 in regulatory T cell expansion and diabetes suppression by zymosan in nonobese diabetic mice.
    Journal of Immunology 185, 2754 -2762 PubMed abstract
  • Hirota, K; Martin, B and Veldhoen, M (2010)
    Development, regulation and functional capacities of Th17 cells.
    Seminars in Immunopathology 32, 3-16 PubMed abstract
  • Murphy, KM and Stockinger, B (2010)
    Effector T cell plasticity: flexibility in the face of changing circumstances.
    Nature Immunology 11, 674-680 PubMed abstract
  • Teixeira-Coelho, M; Cruz, A; Carmona, J; Sousa, C; Ramos-Pereira, D; Saraiva, AL; Veldhoen, M; Pedrosa, J; Castro, AG and Saraiva, M (2010)
    TLR2 deficiency by compromising p19 (IL-23) expression limits Th 17 cell responses to Mycobacterium tuberculosis.
    International Immunology 23, 89-96 PubMed abstract
  • Veldhoen, M and Duarte, JH (2010)
    The aryl hydrocarbon receptor: fine-tuning the immune-response.
    Current Opinion in Immunology 22, 747-752
  • Veldhoen, M and Stockinger, B (2010)
    Response: Characteristics of IL-17-producing γδ T cells.
    Immunity 32, 2 PubMed abstract

[Page last updated 1 Jun 2018]

Gitta Stockinger

Gitta Stockinger
+44 (0)20 379 61600