Vivian Li: Biography

Vivian Li received her BSc (Hons) in Molecular Biotechnology from the Chinese University of Hong Kong. She then obtained her PhD at the University of Hong Kong (Department of Pathology) in 2008, where she researched the molecular mechanism of human colonic development and tumourigenesis. She received the Gold Medal Prize for her PhD thesis.

After completing her PhD study, Vivian was funded by the Croucher Foundation Fellowship to pursue her post-doctoral research training with Hans Clevers at the Hubrecht Institute in the Netherlands. Her work focused on Wnt pathway proteomics and characterising intestinal stem cell genes using newly created transgenic mouse models. She has contributed to the identification of novel Wnt signalling mechanisms at different subcellular levels (receptor, core destruction complex and transcription). During her postdoc studies, she has become familiar with reverse mouse genetics and the recently developed ex vivo organic crypt cultures.

Vivian established her lab at the Medical Research Council National Institute for Medical Research (now part of the Francis Crick Institute) in February 2013. Her group studies Wnt signalling pathway regulation under intestinal homeostasis and tumourigenesis. She also works on intestinal tissue engineering, aiming to translate human intestinal organoid culture for regenerative medicine.

Vivian Li

vivian.li@crick.ac.uk
+44 (0)20 379 61502

  • Qualifications and history
  • 2008 PhD in Department of Pathology, the University of Hong Kong, Hong Kong
  • 2008 Postdoctoral Fellow, Hubrecht Institute, the Netherlands
  • 2013 Group Leader,Medical Research Council National Institute for Medical Research, London, UK
  • 2015 Group Leader, the Francis Crick Institute, London, UK