Justin Molloy: Publications

  • Green, JL; Wall, RJ; Vahokoski, J; Yusuf, NA; Ridzuan, MAM; Stanway, RR; Stock, J; Knuepfer, E; Brady, D; Martin, SR; Howell, SA; Pires, IP; Moon, RW; Molloy, JE; Kursula, I; Tewari, R and Holder, AA (2017)
    Compositional and expression analyses of the glideosome during the Plasmodium life cycle reveal an additional myosin light chain required for maximum motility.
    Journal of Biological Chemistry [Epub ahead of print] PubMed abstract
  • Baboolal, TG; Mashanov, GI; Nenasheva, TA; Peckham, M and Molloy, JE (2016)
    A combination of diffusion and active translocation localizes myosin 10 to the filopodial tip.
    Journal of Biological Chemistry 291, 22373-22385 PubMed abstract
  • Conte, IL; Hellen, N; Bierings, R; Mashanov, GI; Manneville, J-B; Kiskin, NI; Hannah, MJ; Molloy, JE and Carter, T (2016)
    Interaction between MyRIP and the actin cytoskeleton regulates Weibel-Palade body trafficking and exocytosis.
    Journal of Cell Science 129, 592-603 PubMed abstract
  • Khan, S; Conte, I; Carter, T; Bayer, KU and Molloy, JE (2016)
    Multiple CaMKII binding modes to the actin cytoskeleton revealed by single-molecule imaging.
    Biophysical Journal 111, 395-408 PubMed abstract
  • Tabor, A; Weisenburger, S; Banerjee, A; Purkayastha, N; Kaindl, JM; Hübner, H; Wei, L; Grömer, TW; Kornhuber, J; Tschammer, N; Birdsall, NJM; Mashanov, GI; Sandoghdar, V and Gmeiner, P (2016)
    Visualization and ligand-induced modulation of dopamine receptor dimerization at the single molecule level.
    Scientific Reports 6, 33233 PubMed abstract
  • Conte, IL; Cookson, E; Hellen, N; Bierings, R; Mashanov, G and Carter, T (2015)
    Is there more than one way to unpack a Weibel-Palade body?
    Blood 126, 2165-2167 PubMed abstract
  • Khan, SM and Molloy, JE (2015)
    Self-organization: Two's company, three's a crowd.
    Nature Physics 11, 803-804
  • Mashanov, GI (2014)
    Single molecule dynamics in a virtual cell: a three-dimensional model that produces simulated fluorescence video-imaging data.
    Journal of the Royal Society Interface 11, 20140442 PubMed abstract
  • Takagi, Y; Farrow, RE; Billington, N; Nagy, A; Batters, C; Yang, Y; Sellers, JR and Molloy, JE (2014)
    Myosin-10 produces its power-stroke in two phases and moves processively along a single actin filament under low load.
    Proceedings of the National Academy of Sciences of the United States of America 111, E1833-E1842 PubMed abstract
  • Chisty, LT; Toseland, CP; Fili, N; Mashanov, GI; Dillingham, MS; Molloy, JE and Webb, MR (2013)
    Monomeric PcrA helicase processively unwinds plasmid lengths of DNA in the presence of the initiator protein RepD.
    Nucleic Acids Research 41, 5010-5023 PubMed abstract
  • Hussain, S; Molloy, JE and Khan, SM (2013)
    Spatiotemporal dynamics of actomyosin networks.
    Biophysical Journal 105, 1456-1465 PubMed abstract
  • Moody, P; Burlina, F; Martin, SR; Morgan, RE; Offer, J; Smith, MEB; Molloy, JE and Caddick, S (2013)
    Evaluating the use of Apo-neocarzinostatin as a cell penetrating protein.
    Protein Engineering Design and Selection 26, 277-281 PubMed abstract
  • Natkanski, E; Lee, W-Y; Mistry, B; Casal, A; Molloy, JE and Tolar, P (2013)
    B cells use mechanical energy to discriminate antigen affinities.
    Science 340, 1587-1590 PubMed abstract
  • Nenasheva, TA; Neary, M; Mashanov, GI; Birdsall, NJM; Breckenridge, RA and Molloy, JE (2013)
    Abundance, distribution, mobility and oligomeric state of M2 muscarinic acetylcholine receptors in live cardiac muscle.
    Journal of Molecular and Cellular Cardiology 57, 129-136 PubMed abstract
  • Schwarzer, S; Mashanov, GI; Molloy, JE and Tinker, A (2013)
    Using total internal reflection fluorescence microscopy to observe ion channel trafficking and assembly.
    Methods in Molecular Biology 998, 201-208 PubMed abstract
  • Farrow, RE; Green, J; Katismitsoulia, Z; Taylor, WR; Holder, AA and Molloy, JE (2012)
    The mechanism of erythrocyte invasion by the malarial parasite, Plasmodium falciparum.
    Seminars in Cell & Developmental Biology 22, 953-960 PubMed abstract
  • Khan, SM; Ali, R; Asi, N and Molloy, JE (2012)
    Active actin gels.
    Communicative & Integrative Biology 5, 39-42 PubMed abstract
  • Moody, P; Smith, MEB; Ryan, CP; Chudasama, V; Baker, JR; Molloy, J and Caddick, S (2012)
    Bromomaleimide-linked bioconjugates are cleavable in mammalian cells.
    ChemBioChem 13, 39-41 PubMed abstract
  • Nenasheva, TA; Carter, T and Mashanov, GI (2012)
    Automatic tracking of individual migrating cells using low-magnification dark-field microscopy.
    Journal of Microscopy 246, 83-88 PubMed abstract
  • Schuster, M; Treitschke, S; Kilaru, S; Molloy, J; Harmer, NJ and Steinberg, G (2012)
    Myosin-5, kinesin-1 and myosin-17 cooperate in secretion of fungal chitin synthase.
    EMBO Journal 31, 214-227
  • Tominaga, M; Kojima, H; Yokota, E; Nakamori, R; Anson, M; Shimmen, T and Oiwa, K (2012)
    The calcium-induced mechanical change in the neck domain alters the activity of plant myosin XI.
    Journal of Biological Chemistry 287, 30711-30718
  • Fili, N; Toseland, CP; Dillingham, MS; Webb, MR and Molloy, JE (2011)
    A single-molecule approach to visualize the unwinding activity of DNA helicases.
    Methods in Molecular Biology 778, 193-214 PubMed abstract
  • Hewlett, L; Zupančič, G; Mashanov, G; Knipe, L; Ogden, D; Hannah, MJ and Carter, T (2011)
    Temperature-dependence of Weibel-Palade body exocytosis and cell surface dispersal of von Willebrand factor and its propolypeptide.
    PLOS ONE 6, e27314 PubMed abstract
  • Masino, L; Nicastro, G; De Simone, A; Calder, L; Molloy, J and Pastore, A (2011)
    The Josephin domain determines the morphological and mechanical properties of ataxin-3 fibrils.
    Biophysical Journal 100, 2033-2042 PubMed abstract
  • Nenasheva, TA; Mashanov, GI; Peckham, M and Molloy, JE (2011)
    Imaging individual myosin molecules within living cells.
    Methods in Molecular Biology 778, 123-142 PubMed abstract
  • Bee, C; Moshnikova, A; Mellor, CD; Molloy, J; Koryakina, Y; Stieglitz, B; Khokhlatchev, A and Herrmann, C (2010)
    Growth and tumor suppressor novel ras effector 1A (NORE1A) is a regulatory node between ras signaling and microtubule nucleation.
    Journal of Biological Chemistry 285, 16258-16266 PubMed abstract
  • Butt, T; Mufti, T; Humayun, A; Rosenthal, PB; Khan, S; Khan, S and Molloy, JE (2010)
    Myosin motors drive long-range alignment of actin filaments.
    Journal of Biological Chemistry 285, 4964-4974 PubMed abstract
  • Fili, N; Mashanov, GI; Toseland, CP; Batters, C; Wallace, MI; Yeeles, JTP; Dillingham, MS; Webb, MR and Molloy, JE (2010)
    Visualizing helicases unwinding DNA at the single molecule level.
    Nucleic Acids Research 38, 4448-4457 PubMed abstract
  • Hern, JA; Baig, AH; Mashanov, GI; Birdsall, B; Corrie, JET; Lazareno, S; Molloy, JE and Birdsall, NJM (2010)
    Formation and dissociation of M1 muscarinic receptor dimers seen by total internal reflection fluorescence imaging of single molecules.
    Proceedings of the National Academy of Sciences of the United States of America 107, 2693-2698 PubMed abstract
  • Mashanov, GI; Nobles, M; Harmer, SC; Molloy, JE and Tinker, A (2010)
    Direct observation of individual KCNQ1 potassium channels reveals their distinctive diffusive behaviour.
    Journal of Biological Chemistry 285, 3664-3675 PubMed abstract
  • Padgett, MJ; Molloy, J and McGloin, D (editors).
    Optical tweezers: methods and applications.
    Boca Raton, CRC Press, 2010.

[Page last updated 1 Nov 2017]

Justin Molloy

justin.molloy@crick.ac.uk
+44 (0)20 379 62352

  • Qualifications and History
  • BSc, Physiology, University of York, UK
  • PhD Biophysics, University of York, UK
  • 1995 - 2002 Royal Society University Research Fellow, York, UK
  • 2002 - Date Head of Division of Physical Biochemistry, Medical Research Council National Institute for Medical Research (MRC-NIMR), London, UK
  • 2005 - Date Head of Structural Biology Group, MRC-NIMR, London, UK
  • 2015 Group Leader, the Francis Crick Institute, London, UK