Alex Gould: Publications

  • Obata, F; Fons, CO and Gould, AP (2018)
    Early-life exposure to low-dose oxidants can increase longevity via microbiome remodelling in Drosophila.
    Nature Communications 9, 975 PubMed abstract
  • Brandsma, J; Bailey, AP; Koster, G; Gould, AP and Postle, AD (2017)
    Stable isotope analysis of dynamic lipidomics.
    Biochimica et Biophysica Acta 1862, 792-796 PubMed abstract
  • Gilmore, I; West, A; Alexander, M and Gould, A (2017)
    Principles of Systems Biology, No. 24 : Sub-cellular imaging of metabolites with 3D OrbiSIMS.
    Cell Systems 5, 534 PubMed abstract
  • Sawala, A and Gould, AP (2017)
    The sex of specific neurons controls female body growth in Drosophila.
    PLOS Biology 15, e2002252 PubMed abstract
  • Stefana, MI; Driscoll, PC; Obata, F; Pengelly, AR; Newell, CL; MacRae, JI and Gould, AP (2017)
    Developmental diet regulates Drosophila lifespan via lipid autotoxins.
    Nature Communications 8, 1384 PubMed abstract
  • Welte, MA and Gould, AP (2017)
    Lipid droplet functions beyond energy storage.
    Biochimica et Biophysica Acta 1862, 1260-1272 PubMed abstract
  • Cinnamon, E; Makki, R; Sawala, A; Wickenberg, LP; Blomquist, GJ; Tittiger, C; Paroush, Ze and Gould, AP (2016)
    Drosophila Spidey/Kar regulates oenocyte growth via PI3-kinase signaling.
    PLOS Genetics 12, e1006154 PubMed abstract
  • Bailey, AP; Koster, G; Guillermier, C; Hirst, EMA; MacRae, JI; Lechene, CP; Postle, AD and Gould, AP (2015)
    Antioxidant role for lipid droplets in a stem cell niche of Drosophila.
    Cell 163, 340-353 PubMed abstract
  • Makki, R; Cinnamon, E and Gould, AP (2014)
    The development and functions of oenocytes.
    Annual Review of Entomology 59, 405-425 PubMed abstract
  • Prin, F; Serpente, P; Itasaki, N and Gould, AP (2014)
    Hox proteins drive cell segregation and non-autonomous apical remodelling during hindbrain segmentation.
    Development 141, 1492-1502 PubMed abstract
  • Breckenridge, RA; Piotrowska, I; Ng, K-E; Ragan, TJ; West, JA; Kotecha, S; Towers, N; Bennett, M; Kienesberger, PC; Smolenski, RT; Siddall, HK; Offer, JL; Mocanu, MM; Yelon, DM; Dyck, JRB; Griffin, JL; Abramov, AY; Gould, AP and Mohun, TJ (2013)
    Hypoxic regulation of Hand1 controls the fetal-neonatal switch in cardiac metabolism.
    PLOS Biology 11, e1001666 PubMed abstract
  • Lanet, E; Gould, AP and Maurange, C (2013)
    Protection of neuronal diversity at the expense of neuronal numbers during nutrient restriction in the Drosophila visual system.
    Cell Reports 3, 587-594 PubMed abstract
  • Ragan, TJ; Bailey, AP; Gould, AP and Driscoll, PC (2013)
    Volume determination with two standards allows absolute quantification and improved chemometric analysis of metabolites by NMR from submicroliter samples.
    Analytical Chemistry 85, 12046-12054 PubMed abstract
  • Steinhauser, ML; Bailey, AP; Senyo, SE; Guillermier, C; Perlstein, TS; Gould, AP; Lee, RT and Lechene, CP (2012)
    Multi-isotope imaging mass spectrometry quantifies stem cell division and metabolism.
    Nature 481, 516-520 PubMed abstract
  • Cheng, LY; Bailey, AP; Leevers, SJ; Ragan, TJ; Driscoll, PC and Gould, AP (2011)
    Anaplastic lymphoma kinase spares organ growth during nutrient restriction in Drosophila.
    Cell 146, 435-447 PubMed abstract
  • Cognigni, P; Bailey, AP and Miguel-Aliaga, I (2011)
    Enteric neurons and systemic signals couple nutritional and reproductive status with intestinal homeostasis.
    Cell Metabolism 13, 92-104 PubMed abstract
  • Sousa-Nunes, R; Yee, LL and Gould, AP (2011)
    Fat cells reactivate quiescent neuroblasts via TOR and glial insulin relays in Drosophila.
    Nature 471, 508-512 PubMed abstract
  • Grant, J; Saldanha, JW and Gould, AP (2010)
    A Drosophila model for primary coenzyme Q deficiency and dietary rescue in the developing nervous system.
    Disease Models & Mechanisms 3, 799-806 PubMed abstract
  • Sousa-Nunes, R; Cheng, LY and Gould, AP (2010)
    Regulating neural proliferation in the Drosophila CNS.
    Current Opinion in Neurobiology 20, 50-57 PubMed abstract
  • Zhu, D; Jarmin, S; Ribeiro, A; Prin, F; Xie, SQ; Sullivan, K; Briscoe, J; Gould, AP; Marelli-Berg, FM and Gu, Y (2010)
    Applying an adaptive watershed to the tissue cell quantification during T-cell migration and embryonic development.
    Methods in Molecular Biology 616, 207-228 PubMed abstract

[Page last updated 1 Jun 2018]

Alex Gould
+44 (0)20 379 61452

  • Qualifications and history
  • 1990: Ph.D. in developmental genetics. University of Cambridge,  UK
  • 1992: Beit post-doctoral Fellow, Medical Research Council (MRC) National Institute for Medical Research, London, UK
  • 1998: Group leader (Head of Division from 2012), MRC National Institute for Medical Research, London, UK
  • 2015 Group Leader, the Francis Crick Institute, London, UK