Adrian Hayday: Biography

Adrian Hayday trained as a biochemist, undertook PhD studies in tumour virology, and then pursued post-doctoral training at the Massachusetts Institute of Technology where he characterised chromosome translocation breakpoints in human B cell lymphomas, and contributed to the identification of the hitherto unanticipated gamma delta T cell compartment by being the first to describe the T cell receptor gamma chain genes.

In 13 years on the Faculty at Yale, he helped show that gamma delta T cells illustrate a distinct, unrecognised aspect of lymphocyte biology, including the cells' disproportionate association with tissues rather than with lymphoid organs, and their rapid responses to tissue-'stress'.

At a time when tumour immune surveillance was not widely accepted, his lab showed that mice lacking gamma delta T cells are profoundly more susceptible to carcinogens.

His group returned to London in 1998 to establish the Peter Gorer Dept of Immuonbiology at King's College London, then joined the Cancer Research UK London Research Institute (now part of the Francis Crick Institute) as a joint appointee in 2009.

In recent years, his group has developed a strong programme in human immunology, including clinical trials applying gamma delta T cells in immunotherapy. Amongst many honours, he became in 1997 the first biologist to win Yale College's most prestigious prize for scholarship, the William Clyde DeVane Medal.

Adrian Hayday

adrian.hayday@crick.ac.uk
+44 (0)20 379 61884

  • Qualifications and history
  • 1979 PhD, Imperial College London, UK
  • 1982 Postdoctoral, MIT, USA
  • 1985 Faculty, Yale University, USA
  • 1998 King's College London School of Medicine, UK
  • 2009 Established lab at the London Research Institute, Cancer Research UK
  • 2015 Group Leader, the Francis Crick Institute, London, UK