Science news: 2017

Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec

Cancer-causing mutation suppresses immune system around tumours

Mutations in ‘Ras’ genes, which drive 25% of human cancers by causing tumour cells to grow, multiply and spread, can also protect cancer cells from the immune system
12 December 2017

New TB drugs possible with understanding of old antibiotic

Tuberculosis, and other life-threatening microbial diseases, could be more effectively tackled with future drugs, thanks to new research into an old antibiotic.
05 December 2017

Low protein diet in early life increases lifespan in fruit flies

Fruit flies raised on a low protein diet early in life can live over twice as long as their peers.
09 November 2017

New toolkit reveals novel cancer genes

A new statistical model has enabled researchers to pinpoint 27 novel genes thought to prevent cancer from forming, which could help create new cancer treatments that target these genes, and open up other avenues of cancer research.
31 October 2017

Research reveals how pollutants affect early embryo development

Chemicals found in cigarette smoke, factories and incinerators can interfere with the crucial early stages of embryo development
27 October 2017

New bowel cancer drug target discovered

Researchers have discovered a new drug target for bowel cancer that is specific to tumour cells and therefore less toxic than conventional therapies.
17 October 2017

A defence mechanism to kill intestinal worms

Researchers have discovered a mechanism that kills intestinal worms, which affect nearly a third of the world's population as well as livestock.
11 October 2017

Genome editing reveals role of gene important for human embryo development

Researchers have used genome editing technology to reveal the role of a key gene in human embryos in the first few days of development.
20 September 2017

Chemo-boosting drug discovered for leukemia

Drugs developed to treat heart and blood vessel problems could be used in combination with chemotherapy to treat an aggressive form of adult leukemia.
31 August 2017

New technique overcomes genetic cause of infertility

Scientists have created healthy offspring from genetically infertile male mice, offering a potential new approach to tackling a common genetic cause of human infertility.
17 August 2017

A microscope within a microscope

Lucy Collinson leads the Electron Microscopy Science Technology Platform at the Francis Crick Institute. The platform provides expertise in imaging the structures of molecules, cells and tissues at high resolution.
14 August 2017

Partnering with industry to fight malaria

Edgar Deu is looking for new ways to develop antimalarial drugs and to overcome drug resistance among the parasites that cause malaria.
14 August 2017

Putting the brakes on immortal cancer cells

Working with chemists at AstraZeneca, Paola Scaffidi is looking for new drugs to stop cancer cell growth
14 August 2017

New approach makes it easier to find novel drugs

Scientists have created a new way of screening compounds that is more sensitive than existing methods, opening up the possibility of finding new drugs for many diseases.
07 August 2017

Understanding cell segregation mechanisms which help prevent cancer spread

Scientists have uncovered how cells are kept in the right place as the body develops, which may shed light on what causes invasive cancer cells to migrate.
26 July 2017

New study sheds light on disease-busting ‘recycling bins’ in our cells

Scientists have made an important step in understanding how cells keep themselves clean and healthy, with implications for neurodegenerative diseases and cancer.
13 July 2017

New analysis sheds light on mutations in cancer and the immune system

A large-scale analysis reveals how different mutations are seen by the immune system and could help clinicians identify patients likely to benefit from new immunotherapies.
10 July 2017

Scientists find new method to fight malaria

Scientists have discovered a new way to slow down malaria infections, providing a possible new target for antimalarial drugs.
07 July 2017

Scientists find mechanism behind precise spinal cord development

Scientists have uncovered how nerve cells in the spinal cord are organised in precise patterns during embryo development
30 June 2017

Biological fingerprint of tuberculosis meningitis discovered in children

Children with tuberculosis meningitis have a biological fingerprint that can be used to assess the severity of the condition, help decide the best course of treatment, and provide clues for novel treatments.
21 June 2017

Cells change type to help or hinder immunity

In news that may bring hope to asthma sufferers, scientists discover a mechanism that provides a possible new target for allergy treatments.
05 June 2017

Motor neuron disease discovery offers new insights into potential treatment targets

Scientists have discovered how certain forms of motor neuron disease begin and progress, revealing potential new ways to slow down or even stop this process.
30 May 2017

Understanding the architecture of our ‘second brain’

Insights into the organisation of gut nerve cells could help find treatments for gastrointestinal disorders.
19 May 2017

Crick spinout secures $100m collaboration

GammaDelta Therapeutics, a company built on the research of Adrian Hayday and Oliver Nussbaumer from the Crick and King’s College London, has secured a $100m (£77m) collaboration with pharmaceutical giant Takeda.
11 May 2017

A defence mechanism that can trap and kill TB bacteria

New discovery of how cells kill TB bacteria could help in the battle against antibiotic-resistant bacteria
10 May 2017

Pox virus discovery has implications for vaccines and cancer

Crick researchers have made the unexpected discovery that the Vaccinia virus, which was used in the vaccine that eradicated smallpox, needs proteins from the host cells it infects to replicate.
02 May 2017

New study reveals how embryonic cells make spinal cord, muscle and bone

A study sheds new light on the cells that form spinal cord, muscle and bone tissue in mammalian embryos.
27 April 2017

Tracking unstable chromosomes helps predict lung cancer’s return

Scientists at the Francis Crick Institute and UCL have found that unstable chromosomes within lung tumours increase the risk of cancer returning after surgery, and have used this new knowledge to determine the risk of relapse up to a year before the cancer returns.
26 April 2017

Study springs surprise: single gene mutation can lead to variable outcomes

Inactivating the same gene in mice that are virtually genetically identical can result in a wide range of different physical features or abnormalities.
21 April 2017

Controlling amino acids in diet could aid cancer treatment in future

Cutting out certain amino acids – the building blocks of proteins – from the diet of mice slows growth of some tumours and prolongs survival, according to new research.
20 April 2017

Research identifies brain cells that keep mice active

A mouse study provides insight into the brain circuits underlying what motivates us to be physically active
11 April 2017

Enzyme-free Krebs cycle may have been key step in origin of life on Earth

A set of biochemical processes crucial to cellular life on Earth could have originated in chemical reactions taking place on the early Earth four billion years ago.
13 March 2017

New studies show how malaria parasite grows and escapes from red blood cells

Two new studies from the Francis Crick Institute shed light on how the malaria parasite grows inside a host’s red blood cells and breaks out when it’s ready to spread to new host cells.
13 March 2017

Dedicated laboratory for schools opens

The first school groups are learning about science within one of the world’s leading biomedical laboratories.
08 March 2017

TB bacteria can elude our immune response by living inside dead macrophages

The bacteria responsible for tuberculosis (TB) can live on, thriving and replicating, inside human immune cells called macrophages that are sent to hunt them down.
27 February 2017

Steroid reduces risk of complication when treating HIV and TB patients

An inexpensive and readily accessible anti-inflammatory drug reduces the risk of a potentially dangerous complication in patients starting treatment for both TB and HIV.
24 February 2017

Cancer cells hijack healthy cells

An interaction between two proteins enables cancer cells to use the physical forces of healthy cells to start spreading to other parts of the body.
23 February 2017

What happens to gene transcription during DNA damage?

For the first time, scientists have described what happens at the molecular level when gene transcription slows down in response to DNA damage in a cell.
16 February 2017

Genes linked to malaria parasites’ ability to persist in the body

The ability of malaria parasites to persist in the body for years is linked to the expression of a set of genes from the pir gene family, scientists have found.
06 February 2017

More evidence for eating your greens

Cruciferous vegetables contain nutrients that might reverse susceptibility to gut pathogens in people at increased risk of infections.
01 February 2017

Yeast study reveals how CDK protein controls cell division timing

A study in yeast proposes an explanation for the timing of action of CDK – the ‘master regulator’ of cell division.
26 January 2017

New insights into infertility-causing sex chromosome disorders

Research carried out by Francis Crick Institute scientists provides new insights into sex chromosome disorders which typically cause infertility.
26 January 2017

Supporting actors take lead role as our brains age

Brain cells that support neurons change most as we get older, suggesting a new focus for dementia research
10 January 2017

Researchers reveal how cancer cells cope with genetic chaos

Scientists have uncovered how tumours are able to grow despite significant damage to the structure and number of their chromosomes, according to two new studies.
09 January 2017