A protein on the surface of the seasonal flu virus H3N2 has changed over the past decade, reducing its affinity for binding to human host cells.
26 December 2012
The discovery that enzymes previously thought to sense nutrients in our bodies can also ‘turn off’ the usual cell growth regulation pathway that prevents tumours.
23 December 2012
The discovery of a direct link between a gene that enables stem cells to keep renewing themselves and a previously unrelated gene involved in human cancers.
20 December 2012
Combining knowledge about small gene mutations and protein structures offers a new way to study complex diseases that result from many such mutations.
29 November 2012
A major survey of variations in malaria genes has identified potential targets for a vaccine against the disease.
23 November 2012
A new way of identifying antigens on the bacteria that causes TB may help in the search for a vaccine.
19 November 2012
LRI scientist won the Royal Micrograph Society biennial competition for her image of the appendages that enable ragworms to move
30 October 2012
Ancient viruses that have become part of our DNA may be able to reactivate and cause infections and even cancer.
24 October 2012
The discovery of a unique enzyme in the malaria parasite may lead to new strategies to prevent the spread of the disease.
20 September 2012
Scientists at Cancer Research UK’s London Research Institute have found an unexpected role for a protein that helps viruses to invade host cells.
13 September 2012
Studying mice, researchers have found the first evidence in mammals of a battle between the X and Y chromosomes, which changes the balance of male and female offspring.
13 September 2012
A mouse model of SIDS (cot death) has linked low oxygen in babies with heart changes and death.
12 September 2012
Adding vitamin D to antibiotic treatment may speed tuberculosis recovery and reduce lung damage.
04 September 2012
Human brains contain billions of nerve cells, or neurons. There are huge variations in the structure and form of these neurons, and even vast differences in properties within the same structural groups.
22 July 2012
A new study of thiopurines – drugs used to treat cancer and as immunosuppressants – has uncovered more about how they work and suggested possible new ways they could be used.
11 July 2012
Uncovered: an elusive marsupial gene linked to diseases in humans
17 June 2012
Scientists have discovered that bacteria have evolved a way to safeguard their most important genes against random mutations. The work provides insights into how disease-causing mutations arise in humans, such as those that occur in cancer.
03 May 2012
Scientists at Cancer Research UK have revealed a possible new treatment for a common and aggressive form of lung cancer.
26 April 2012
Partnership finds new drug candidates for the tropical diseases malaria and leishmaniasis
24 April 2012
A study published in the New England Journal of Medicine has found that taking a sample from just one part of a tumour may not give a full picture of its ‘genetic landscape’.
07 March 2012
Guidance aimed at helping The Francis Crick Institute to accelerate the benefits to patients from its work has been published.
27 January 2012
How genes interact to control the development of cells into tissues
20 January 2012