Science news: 2012

Jan | Mar | Apr | May | Jun | Jul | Sep | Oct | Nov | Dec

Common seasonal flu strain binds human host cells less strongly than a decade ago

A protein on the surface of the seasonal flu virus H3N2 has changed over the past decade, reducing its affinity for binding to human host cells.
26 December 2012

Enzymes implicated in unchecked cancer growth

The discovery that enzymes previously thought to sense nutrients in our bodies can also ‘turn off’ the usual cell growth regulation pathway that prevents tumours.
23 December 2012

Surprising link between stem cell and cancer genes

The discovery of a direct link between a gene that enables stem cells to keep renewing themselves and a previously unrelated gene involved in human cancers.
20 December 2012

Combining information about proteins and genes to improve disease insights

Combining knowledge about small gene mutations and protein structures offers a new way to study complex diseases that result from many such mutations.
29 November 2012

Malaria vaccine could target variant parasite proteins

A major survey of variations in malaria genes has identified potential targets for a vaccine against the disease.
23 November 2012

New approach to finding TB antigens may lead to vaccine

A new way of identifying antigens on the bacteria that causes TB may help in the search for a vaccine.
19 November 2012

Dancing parapodia image wins top prize

LRI scientist won the Royal Micrograph Society biennial competition for her image of the appendages that enable ragworms to move
30 October 2012

Ancient viruses in our DNA can reactivate and cause cancer

Ancient viruses that have become part of our DNA may be able to reactivate and cause infections and even cancer.
24 October 2012

Enzyme discovery may lead to new ways to fight malaria

The discovery of a unique enzyme in the malaria parasite may lead to new strategies to prevent the spread of the disease.
20 September 2012

Trojan horse that helps virus invade a cell also plays a key role in spreading infection

Scientists at Cancer Research UK’s London Research Institute have found an unexpected role for a protein that helps viruses to invade host cells.
13 September 2012

Sex chromosome battle leads to more female mice

Studying mice, researchers have found the first evidence in mammals of a battle between the X and Y chromosomes, which changes the balance of male and female offspring.
13 September 2012

GM mice to help unravel mystery of cot death

A mouse model of SIDS (cot death) has linked low oxygen in babies with heart changes and death.
12 September 2012

Vitamin D aids TB recovery

Adding vitamin D to antibiotic treatment may speed tuberculosis recovery and reduce lung damage.
04 September 2012

Information processing in brain circuits influences its cellular properties

Human brains contain billions of nerve cells, or neurons. There are huge variations in the structure and form of these neurons, and even vast differences in properties within the same structural groups.
22 July 2012

Cancer and immune drug insights suggest new uses

A new study of thiopurines – drugs used to treat cancer and as immunosuppressants – has uncovered more about how they work and suggested possible new ways they could be used.
11 July 2012

Identifying a marsupial gene linked to human disease

Uncovered: an elusive marsupial gene linked to diseases in humans
17 June 2012

How bacteria protect key genes from mutation and implications for cancer

Scientists have discovered that bacteria have evolved a way to safeguard their most important genes against random mutations. The work provides insights into how disease-causing mutations arise in humans, such as those that occur in cancer.
03 May 2012

Existing drugs could target smokers’ lung cancer

Scientists at Cancer Research UK have revealed a possible new treatment for a common and aggressive form of lung cancer.
26 April 2012

Partnership speeds malaria and leishmaniasis drug discovery

Partnership finds new drug candidates for the tropical diseases malaria and leishmaniasis
24 April 2012

Cancer genes differ in different parts of a tumour

A study published in the New England Journal of Medicine has found that taking a sample from just one part of a tumour may not give a full picture of its ‘genetic landscape’.
07 March 2012

Accelerating benefits to patients

Guidance aimed at helping The Francis Crick Institute to accelerate the benefits to patients from its work has been published.
27 January 2012

The secret of cell structures in developing embryos

How genes interact to control the development of cells into tissues
20 January 2012